Where is the earliest site for intraosseous infusion located?

The earliest site for intraosseous infusion is located at the anterior tibia, just below the tibial tuberosity. This site is preferred because it provides easy access to the medullary cavity of the bone, allowing for effective delivery of fluids and medications directly into the vascular system. The anterior tibia is also relatively superficial and easier to access in emergency situations, making it a common site for intraosseous access, especially in pediatric patients.

Other potential sites for intraosseous infusion, such as the medial malleolus, distal radius, and femoral head, may be used in specific circumstances or when the primary site is unavailable, but the anterior tibia remains the default and earliest recommended site for establishing access. This site facilitates rapid infusion, which is critical in life-threatening situations where intravenous access may be challenging or delayed.